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Foundation Model
scGPT
Generative pre-trained transformer for single-cell biology. Pre-trained on 33M+ cells from CELLxGENE.
Overview
scGPT is a foundation model for single-cell biology built upon a generative pre-trained transformer architecture. It is trained on over 33 million human cells from the CELLxGENE database and can be fine-tuned for various downstream tasks including cell type annotation, gene perturbation prediction, multi-omics integration, and batch correction.
Publication
scGPT: Toward Building a Foundation Model for Single-Cell Multi-Omics Using Generative AI